Pharmacokinetic models
Choose the correct answer for each question.
1
When a drug is adminstered, it initially distributes into the:
Central volume
Total volume
Peripheral volume
Apparent volume
2
One compartment models are used for drugs which equilibrate:
With Vc
With Vd
Slowly
Rapidly
3
A serum level plot of a two compartment models using a log scale y-axis yields a:
Straight line
Biphasic line
Neither
4
Misinterpretation of SDC data may occur for some drugs if samples are drawn during:
Excretion
Distribution
Clearance
Steady-state
5
Vancomycin is best modeled with:
A one-compartment first-order model.
A one-compartment second-order model.
A two-compartment first-order model.
A two-compartment second-order model.